Exemestane, on the basis of which developed the drug Exedrol вЂ“ the substance of new generation, designed to block the enzymes responsible for the aromatization. It inhibits at least 85% of estrogens in the human body, and this process is irreversible.Description of Exedrol
the First analogue of the drug was developed in 1999, the year for the treatment of cancer tumors of the breast in women included in the postmenopause. It is particularly effective in cases when the disease progresses, despite treatment with tamoxifen.
What is that Exedrol?! What is it used for men in bodybuilding (athletes)?! The answer is simple вЂ“ the drug is a modern aromatase inhibitor, suppresses its activity on the conversion of Testosterone into estrogen.
On a course of steroids Exedrol (Balkan Pharmaceuticals) is needed to prevent side effects from the use of aromatizers steroids. Its action is fundamentally different from the action of tamoxifen, which does not affect the aromatization process, and interact with cellular estrogen receptors, preventing the estrogen to connect them.
Hexadrol tablets effect manifests differently, it affects the process of aromatization, leading to its suppression. The structure of the drug is similar to natural steroid Androstenedione. The process of irreversible binding to active enzymes hormones and their transformation into inactive. By themselves, tablets are only minor androgenic activity, with no signs of estrogenic or progestogenic.
Detailed instructions for medical use Exedrol (exemestane) posted on the Forum. In fact, it is the drug, the last full clinical studies and be formally admitted to the use of people. The drug is original, so no doubt the quality of its production, as a rule, is not necessary.
Exedrol differs significantly from the typical class of drugs aromatase inhibitors. Its effect is irreversible/permanent, whereas the first aromatase inhibitors have had only temporary effectiveness.
Side effects Exedrol can occur with varying severity. It can be fatigue, insomnia, depression, nausea, headaches, high cholesterol, and other violations. When individual sensitivity to the drug, its use is not recommended (side effects increase).
the Cost of similar tablets is high enough, but their effectiveness is not in doubt. The athlete who wants to rid themselves of side effects of the steroids the type of gynecomastia, edema and accumulation of liquid, it is necessary to consider its application.
the effect of the substance selective (selective), it has no effect on the biosynthesis of the hormones cortisol and aldosterone, so there is no need to use of glucocorticoids and mineralocorticoids to compensate.How to take Exedrol
the Drug is indicated for the prevention of adverse effects of steroids in a dosage of 0.5-1 tablets (12-25 mg) a day or two. If side effects such as gynecomastia are already obvious and pronounced, the dose should be increased to 25 mg (1 pill) each day until the disappearance of the manifestations of estrogenic side effects. It should be noted that in neglected cases even this drug is not able to cope with gynecomastia, surgical intervention is necessary.
the Use of Exedrol (Balcan) simultaneously with a meal or immediately after it enhances the bioavailability of the substance is 40%, the maximum concentration in the blood, it reaches on average 2 hours after ingestion.
Dosage of Hexadrol for athletes suffering from diseases of the kidneys or liver, remains the same as for able-bodied athletes. But in such cases, the systemic effect of the drug will be enhanced 2-3 times. Therefore, it must be applied with caution, if necessary, reducing the dose or refusing admission.
the Course of Axedale as a preventive measure usually lasts 2-4 weeks, for the treatment of manifested side effects of steroids is prolonged until the disappearance of signs of the action of estrogen (disappearance of symptoms).
in compliance With the daily dose of 25 mg adverse effects of the drug are usually mild or even negligible. Tablets fit athletes of any level of training, but more often consult experienced professionals, who carry out do